What exactly is TB-500, and why do research programs pick the 10mg tier?
TB-500 is the 43-amino-acid synthetic fragment corresponding to the actin-binding domain of thymosin beta-4, studied in pre-clinical models of actin monomer sequestration, cellular migration, and tissue remodeling. The 10mg per vial tier is picked by programs running multi-arm cohorts because a single vial supports several weeks of working-stock draws after 1 to 2 mL reconstitution.
What does this specific lot’s CoA cover?
Every TB-500 lot is characterised by reverse-phase HPLC for purity and by LC-MS matched to the theoretical 4963.4 Da mass. Lot certificates are attached to the product record as each release completes.
How do I reconstitute a 10mg TB-500 vial?
- Allow the vial to equilibrate to room temperature.
- Swab the stopper with an alcohol pad.
- Draw 1 to 2 mL of bacteriostatic water and add it slowly along the vial wall.
- Rotate the vial gently until the cake fully dissolves — do not shake, and avoid vortexing.
- Refrigerate at 2 to 8 °C. Use the reconstituted solution within 30 days.
Should I order the 5mg or 10mg tier?
The 5mg tier is scaled for small-cohort or method-development runs; the 10mg tier reduces reconstitution overhead when a program is running the same working concentration across several weeks of experiments. Both share the same lot-release specification and lyophilization protocol.
How does TB-500 compare with BPC-157?
TB-500 is the actin-binding thymosin beta-4 fragment, while BPC-157 is a 15-amino-acid pentadecapeptide fragment derived from a gastric juice protein. The two are frequently co-studied in tissue-repair models because the in-vitro mechanisms attributed to each — actin monomer sequestration versus cytoprotection and angiogenic modelling — are non-overlapping. Prescott stocks both individually and as the BB10 5mg + 5mg blend.
What ships in the box, and how fast?
- 10 lyophilized TB-500 vials at 10mg each
For research use only. Orders placed before 14:00 PT ship the same business day from the British Columbia facility, with typical Canadian delivery in 2 to 4 business days.