What exactly is KPV, and why do research programs pick the 10mg tier?
KPV is the C-terminal Lys-Pro-Val tripeptide of α-melanocyte-stimulating hormone, studied in pre-clinical models of NF-κB-mediated inflammatory signalling and mucosal-barrier response. The 10mg per vial tier is selected by teams running larger cohorts or multi-timepoint designs where the 5mg vial would force redundant reconstitutions to reach the required working-stock volume.
What does this specific lot’s CoA cover?
KPV lots are released after reverse-phase HPLC characterisation and LC-MS confirmation against the 342.5 Da theoretical mass. Lot certificates attach to the product record as each release clears.
How do I reconstitute a 10mg KPV vial?
- Let the vial come to room temperature — sudden cold-to-warm shifts risk moisture ingress.
- Wipe the septum with an alcohol swab.
- Add 1 to 2 mL of bacteriostatic water down the inside wall in a single steady motion.
- Invert the vial gently until the cake fully clears; KPV dissolves quickly at these mass loads.
- Refrigerate at 2 to 8 °C and finish within 30 days.
Should I order the 5mg or 10mg tier?
The 5mg tier is standard for programs studying KPV in isolation on smaller cohorts. The 10mg tier makes sense when KPV is being run at higher working concentrations, when the same lot needs to cover multi-arm designs, or when the reconstitution volume otherwise becomes inconveniently small in the 5mg vial.
How does KPV compare with the parent α-MSH sequence?
The full α-MSH molecule is a 13-residue peptide whose activity spans multiple melanocortin receptors, whereas KPV is the terminal Lys-Pro-Val tripeptide reported to retain the anti-inflammatory arm without receptor-driven pigmentation signalling. That signalling separation is exactly why KPV is popular in NF-κB pathway research.
What ships in the box, and how fast?
- 10 lyophilized KPV vials at 10mg each
For laboratory research use only. Same-day dispatch from British Columbia when the order is placed before 14:00 PT; typical Canadian arrival is 2 to 4 business days after ship notification.