What exactly is Semax, and why do research programs pick the 10mg tier?
Semax is a synthetic heptapeptide derived from the ACTH(4-10) fragment, extended at the C-terminus with a Pro-Gly-Pro tail (full sequence: Met-Glu-His-Phe-Pro-Gly-Pro) to resist enzymatic degradation. It is studied in pre-clinical models for BDNF-expression modulation and downstream neurotrophic effects. The 10mg per vial tier gives enough working stock for a complete learning-and-memory-model cohort after 1 to 2 mL reconstitution.
What does this specific lot’s CoA cover?
Each Semax lot is independently assayed by reverse-phase HPLC for purity and by mass-spectrometry for identity confirmation against the theoretical mass of the seven-residue ACTH(4-10) analog. Lot-specific certificates of analysis are being catalogued and will be publicly listed on the product page as they come online.
How do I reconstitute a 10mg Semax vial?
- Alcohol-swab the stopper and let the alcohol evaporate.
- Draw 1 to 2 mL of bacteriostatic water into a sterile syringe.
- Trickle the diluent down the vial wall so the stream does not disturb the peptide cake directly.
- Rotate the vial slowly until the solution clarifies. Do not shake.
- Cap and store the reconstituted vial at 2 to 8 °C for up to 30 days.
Semax vs Selank: how do research programs pick between them?
Semax and Selank are both Russian-origin heptapeptides but sit on different sides of a nootropic-model bench. Semax, an ACTH(4-10) fragment, is the natural pick when the readout of interest is BDNF, NGF, or general neurotrophic signalling in learning-and-memory paradigms. Selank, a tuftsin analog, is chosen when the endpoint is anxiety-related behavioural output driven through GABAergic-adjacent pathways. If a protocol wants to probe cognition and stress-response in the same arm, some programs run them side-by-side or reach for the Adamax blend that includes both.
How does the ACTH(4-10) lineage shape handling?
Semax retains the ACTH(4-10) melanocortin sequence but the Pro-Gly-Pro tail eliminates the classical corticotropic activity of the parent hormone, so the pre-clinical literature treats Semax as a neurotrophic tool rather than a stress-axis modulator. From a wet-lab standpoint that means the same general handling as other heptapeptides in the catalogue: reconstitute with bacteriostatic water, hold at 2 to 8 °C, and finish reconstituted material within 30 days.
What ships in the box, and how fast?
- 10 lyophilized Semax 10mg vials
Orders placed before 14:00 PT ship the same business day from our British Columbia facility. Canadian orders arrive in 2 to 4 business days after dispatch.
