What exactly is Melanotan-1, and why do research programs pick the 10mg tier?
Melanotan-1 (MT-1) is a synthetic α-MSH analog stabilised by a lactam bridge that confers metabolic resistance versus the native peptide, studied in pre-clinical models for melanocortin-1-receptor engagement and downstream pigmentation pathways. The 10mg per vial tier provides ample working stock for multi-week receptor-binding or pigmentation-model protocols after 1 to 2 mL reconstitution.
What does this specific lot’s CoA cover?
Each Melanotan-1 lot is independently assayed by reverse-phase HPLC for purity and by mass-spectrometry for identity against the theoretical mass of the cyclic analog, with special attention to the lactam-bridge integrity that distinguishes MT-1 from linear α-MSH. Lot-specific certificates of analysis are being catalogued and will be publicly listed on the product page as they come online.
How do I reconstitute a 10mg Melanotan-1 vial?
- Swab the vial stopper with alcohol and let it dry fully.
- Draw 1 to 2 mL of bacteriostatic water into a sterile syringe.
- Angle the needle so the diluent travels down the vial wall rather than blasting the cake directly.
- Turn the vial end-over-end slowly until the solution clarifies. Do not shake or vortex.
- Store the reconstituted vial at 2 to 8 °C and use within 30 days.
How does Melanotan-1 differ from Melanotan-II at the receptor level?
MT-1 is designed for selective activity at the MC1R subtype, which is the melanocortin receptor most closely tied to pigmentation biology. Melanotan-II (not stocked in the Prescott catalogue) is a broader melanocortin agonist active across MC1R, MC3R, MC4R, and MC5R, so its published pre-clinical profile touches appetite, sexual-response, and cardiovascular endpoints in addition to pigmentation. Programs specifically studying MC1R biology in isolation reach for MT-1; programs interested in the broader melanocortin family reach for MT-II.
What handling considerations apply to the lactam-bridge structure?
The cyclic lactam bridge that makes MT-1 metabolically stable also makes it slightly slower to dissolve than a linear peptide of the same mass. Allow the reconstituted vial an extra minute or two of gentle swirling before drawing working aliquots, and protect the reconstituted solution from prolonged room-temperature exposure.
What ships in the box, and how fast?
- 10 lyophilized Melanotan-1 10mg vials
Orders placed before 14:00 PT ship the same business day from our British Columbia facility. Canadian orders arrive in 2 to 4 business days after dispatch.